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Series GSE123332 Query DataSets for GSE123332
Status Public on Dec 05, 2018
Title Follicular helper T cells enhance autoimmunity through Ascl-2 in a murine model for Sjögren’s syndrome
Organism Mus musculus
Experiment type Expression profiling by array
Summary We investigated how Tfh cells contribute to the breakdown of peripheral immune tolerance and the formation of autoimmune lesions in a murine model of SS. Our results indicate a yet unreported mechanism of autoreactive response through Tfh cells in a SS model mouse, and it will be supportive for understanding the pathogenesis of autoimmunity.
Overall design Two-condition experiment, purified CD4+ CD25- T cells from spleen of non-thymectomied NFS/sld (Control) vs. purified CD4+ CD25- T cells from spleen of thymectomied NFS/sld (SS model).
Contributor(s) Otsuka K, Yamada A, Inagaki A, Arakaki R, Ushio A, Ishimaru N
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Submission date Dec 04, 2018
Last update date Dec 06, 2018
Contact name Naozumi Ishimaru
Phone 0886337328
Organization name Tokushima University Graduate School
Department Oral Molecular Pathology
Street address Kuramoto
City Tokushima
ZIP/Postal code 7708504
Country Japan
Platforms (1)
GPL11202 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)
Samples (4)
GSM3500932 nonTX,CD25+
GSM3500933 TX,CD25+
GSM3500934 nonTX,CD25-
BioProject PRJNA508374

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE123332_RAW.tar 7.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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