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| Status |
Public on Jun 01, 2020 |
| Title |
Expression Data from Cerulein Treated Pancreas |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
IFRD1 is required for reserve stem cell proliferation in multiple tissues. Repeated cerulein treatment causes damage and induces proliferation in otherwise terminally differentiated pancreatic acinar cells.
We used microarrays to detail gene expression changes in IFRD1 null mice treated with cerulein compared to WT mice treated with cerulein.
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| |
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| Overall design |
Adult mouse pancreatic tissue was harvested at 5 days post cerulein injection for RNA extraction and hybridization on Affymetrix microarrays. We aimed to isolate tissue during the proliferative phase of the pancreatic injury response.
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| |
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| Contributor(s) |
Lewis MA, Mills JC |
| Citation(s) |
32768422 |
| |
| Submission date |
Oct 29, 2018 |
| Last update date |
Aug 31, 2020 |
| Contact name |
Jason C Mills |
| E-mail(s) |
jason.mills@bcm.edu
|
| Phone |
7137984607
|
| Organization name |
Baylor College of Medicine
|
| Department |
Gastroenterology, Medicine
|
| Street address |
One Baylor Plaza
|
| City |
Houston. |
| State/province |
T |
| ZIP/Postal code |
77401 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
|
| Samples (4)
|
| GSM3450017 |
WT adult pancreas at D5, biological rep 1 |
| GSM3450018 |
WT adult pancreas at D5, biological rep 2 |
| GSM3450019 |
IFRD1_KO adult pancreas at D5, biological rep 1 |
| GSM3450020 |
IFRD1_KO adult pancreas at D5, biological rep 2 |
|
| Relations |
| BioProject |
PRJNA499083 |
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