|
| Status |
Public on Oct 20, 2018 |
| Title |
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In comparison with exosomal mRNAs in CSF from four patients with amyotrophic lateral sclerosis, 543 genes were significantly changed, as represented by CUEDC2.
|
| |
|
| Overall design |
Signatures of CSF exosomal mRNAs were then compared between four normal healthy donors and four sporadic amyotrophic lateral sclerosis patients to identify disease-related biomarkers.
|
| |
|
| Contributor(s) |
Otake K, Kamiguchi H, Hirozane Y |
| Citation(s) |
30630471 |
| |
| Submission date |
Oct 19, 2018 |
| Last update date |
Mar 26, 2019 |
| Contact name |
Kentaro Otake |
| E-mail(s) |
kentarou.ootake@takeda.com
|
| Phone |
+81-466-32-1322
|
| Organization name |
Takeda Pharmaceutical Company Limited
|
| Department |
Neuroscience Drug Discovery Unit
|
| Lab |
Innovative Biology Laboratories
|
| Street address |
26-1, Muraoka-Higashi 2-Chome
|
| City |
Fujisawa |
| State/province |
Kanagawa |
| ZIP/Postal code |
251-8555 |
| Country |
Japan |
| |
|
| Platforms (2) |
| GPL15520 |
Illumina MiSeq (Homo sapiens) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA497536 |
| SRA |
SRP166162 |
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