|
| Status |
Public on Nov 19, 2018 |
| Title |
JunB modulates an IRF4-dependent transcriptional program to regulate homeostasis and suppressive functions of effector regulatory T cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
To understand molecular mechanisms by which JunB regulates Treg function, we performed RNA-seq and ChIP-seq analyses of JunB-deficient and control Treg cells (CD4+ CD25hi).
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
RNA-seq analysis of WT and JunB-deficient Treg cells.
ChIP-seq analysis of JunB,BATF and IRF4 in in vitro-activated Treg cells.
Refer to individual Series
|
| |
|
| Citation(s) |
30559442 |
| |
| Submission date |
Oct 16, 2018 |
| Last update date |
Mar 19, 2019 |
| Contact name |
Hiroki Ishikawa |
| E-mail(s) |
hiroki.ishikawa@oist.jp
|
| Organization name |
Okinawa Institute of Science and Technology Graduate University
|
| Lab |
Immune signal unit
|
| Street address |
1919-1 Tancha
|
| City |
Onna-son,Kunigami-gun |
| ZIP/Postal code |
904-0495 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (10)
|
|
| This SuperSeries is composed of the following SubSeries: |
| GSE121293 |
JunB modulates an IRF4-dependent transcriptional program to regulate homeostasis and suppressive functions of effector regulatory T cells [RNA-Seq] |
| GSE121294 |
JunB modulates an IRF4-dependent transcriptional program to regulate homeostasis and suppressive functions of effector regulatory T cells [ChIP-Seq] |
|
| Relations |
| BioProject |
PRJNA496595 |
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