|
| Status |
Public on Oct 12, 2018 |
| Title |
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Methylation profiling by high throughput sequencing
|
| Summary |
In this study we show that ascorbate (vitamin C) shifts the hydroxymethylome and transcriptome in RPE cells, and downregulates expression of VEGF.
|
| |
|
| Overall design |
Examination of transcriptome and hydroxymethylome in vitamin C treated or control ARPE-19 cells
|
| |
|
| Contributor(s) |
Wang G, Sant DW, Camarena V |
| Citation(s) |
30025088 |
| |
| Submission date |
Oct 11, 2018 |
| Last update date |
Mar 21, 2019 |
| Contact name |
David Wayne Sant |
| E-mail(s) |
dwsant@noordacom.org
|
| Phone |
3853758672
|
| Organization name |
Noorda College of Osteopathic Medic
|
| Department |
Biomedical Informatics
|
| Lab |
Kyle Bills
|
| Street address |
1712 South East Bay Blvd, Building 5 Suite 300
|
| City |
Provo |
| State/province |
UT |
| ZIP/Postal code |
84606 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (14)
|
|
| Relations |
| BioProject |
PRJNA495826 |
| SRA |
SRP165215 |
Less...
More...