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Status |
Public on Jul 12, 2008 |
Title |
Gene Expression Profiling Separates Chromophobe Renal Cell Carcinoma from Oncocytoma |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
This study aims to compare gene expression profiles of chromophobe renal cell carcinoma (RCC) and benign oncocytoma, aiming at identifying differentially expressed genes.
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Overall design |
Nine cases each of chromophobe RCC and oncocytoma were analyzed by oligonucleotide microarray. Candidate genes that showed consistent differential expression were validated by RT-PCR using 25 fresh-frozen and 15 formalin-fixed paraffin-embedded tumor samples. Immunohistochemical analysis was also performed for two selected gene products, Claudin 8 and MAL2.
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Contributor(s) |
Rohan S, Tu JJ, Kao J, Mukherjee P, Campagne F, Zhou XK, Hyjek E, Alonso MA, Chen Y |
Citation(s) |
17145811 |
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Submission date |
Jul 11, 2008 |
Last update date |
Mar 25, 2019 |
Contact name |
Piali Mukherjee |
E-mail(s) |
pim2001@med.cornell.edu
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Organization name |
Weill Cornell Medicine
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Department |
Medicine
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Lab |
Epigenomics Core
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Street address |
1300 York Ave. C-545
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City |
NEW YORK |
State/province |
New York |
ZIP/Postal code |
10065 |
Country |
USA |
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Platforms (1) |
GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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Samples (18)
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Relations |
BioProject |
PRJNA113527 |