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| Status |
Public on Apr 01, 2019 |
| Title |
Comparative gene expression analysis between wild-type (WT) and Cables2-deficient epiblast-like cells (EpiLCs). |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We found that Cables2 physically interacts with Smad2 and beta-catenin, and enhances their transcriptional activities. To identify the target genes that are regulated by Cables2 together with Smad2 and/or beta-catenin, we conducted a comparatvie RNA-seq experiment between WT- and Cables2-deficient EpiLCs.
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| Overall design |
mRNA expression profiles of WT- and Cables2-deficient EpiLCs were generated by RNA sequencing using the NextSeq 500 (Illumina)
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| Contributor(s) |
Iseki H, Dinh TH, Muratani M, Sugiyama F |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 24, 2018 |
| Last update date |
Apr 01, 2019 |
| Contact name |
Hiroyoshi Iseki |
| Organization name |
University of Tsukuba
|
| Street address |
1-1-1 Tennodai
|
| City |
Tsukuba |
| State/province |
Ibaraki |
| ZIP/Postal code |
305-8575 |
| Country |
Japan |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA492888 |
| SRA |
SRP162451 |
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