|
| Status |
Public on Sep 12, 2019 |
| Title |
IL-1 inhibition in systemic sclerosis skin. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
IL-1 has been implicated in various fibrotic diseases. This randomized, Placebo-Controlled trial we examine the effect of il1-b inhibition on skin expression.
We used microarrays to explore gene expression changes in the Rilonacept clinical trial
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| |
|
| Overall design |
Patients with diffuse cutaneous systemic sclerosis had biopsies taken prior and post treatment.
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| |
|
| Contributor(s) |
Mantero JC, Lafyatis R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 13, 2018 |
| Last update date |
Sep 14, 2019 |
| Contact name |
Julio C Mantero |
| Organization name |
Boston University School of Medicine
|
| Department |
Rheumatology
|
| Street address |
72 E Concord St
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02118 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL25577 |
[HG-U133A_2] Affymetrix Human Genome U133A Array (HGU133A2 Hs ENTREZG 21.0.0) |
|
| Samples (32)
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|
| Relations |
| BioProject |
PRJNA490744 |
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