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| Status |
Public on Mar 12, 2019 |
| Title |
Fibroblast RNA-Seq data from three genodermatoses (RDEB, XPC and KS) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Recessive dystrophic epidermolysis bullosa, Kindler syndrome and xeroderma pigmentosum C, are three cancer-prone genodermatoses whose causal genetic mutations cannot fully explain, on their own, the array of associated phenotypic manifestations. Recent evidence highlights the contributing role of the stromal microenvironment in the pathology of these disorders. To investigate common mechanisms that contribute to the pathogenic role played by dermal fibroblasts, we conducted a comparative gene expression analysis by RNA-Seq.
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| Overall design |
3 healthy controls, 9 RDEB, 3 XPC and 3 KS patients
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| Contributor(s) |
Leon C, del Rio M |
| Citation(s) |
30693469 |
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| Submission date |
Sep 05, 2018 |
| Last update date |
Jun 11, 2019 |
| Contact name |
carlos leon |
| E-mail(s) |
cleon@ing.uc3m.es
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| Phone |
916248211
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| Organization name |
UC3M
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| Department |
Bioengineering
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| Street address |
Avenida Universidad 30
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| City |
Leganes |
| State/province |
Madrid |
| ZIP/Postal code |
28911 |
| Country |
Spain |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA489425 |
| SRA |
SRP159647 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE119501_Counts_matrix.xlsx |
5.2 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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