|
| Status |
Public on Mar 22, 2019 |
| Title |
Expression data from mouse optic nerve and optic tract |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
A membrane protein SIRPα (CD172a) interacts with another membrane protein CD47 and thereby constitutes a cell–cell contact signal.
To investigate the functional role of CD47-SIRPα signal in the brain, we analyzed the effect of genetic ablation of CD47-SIRPα signal on the gene expression profile in specific brain regions by the use of microarrays.
|
| |
|
| Overall design |
Total RNAs were prepared from the white matter (optic nerve and optic tract) of wild-type or CD47 knockout mice. Total RNAs from five (wild-type) and four (CD47 knockout) different genotype-matched animals were pooled and subjected to the analysis on Affymetrix Gene Chip.
|
| |
|
| Contributor(s) |
Ohnishi H |
| Citation(s) |
30910011 |
| |
| Submission date |
Aug 20, 2018 |
| Last update date |
Jul 10, 2019 |
| Contact name |
Hiroshi Ohnishi |
| Organization name |
Gunma University Graduate School of Health Sciences
|
| Department |
Department of Laboratory Sciences
|
| Street address |
3-39-22 Showa-machi
|
| City |
Maebashi |
| State/province |
Gunma |
| ZIP/Postal code |
371-8514 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
|
| Samples (2) |
| GSM3348013 |
white matter sample from wild-type mice |
| GSM3348014 |
white matter sample from CD47 null mice |
|
| Relations |
| BioProject |
PRJNA486823 |
