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| Status |
Public on Aug 02, 2018 |
| Title |
SNON and Arkadia (RNF111) regulate TGFβ-SMAD2/3 dose-dependent responses |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The purpose of this RNA-seq experiment was to identify Activin A target genes that were differentially expressed in wild type and Arkadia null mouse embryonic stem cells (ESC). We performed the RNA sequencing experiment in two different wt and Arkadia-/- ESC under conditions of signalling inhibition SB431542 (SB; T0) and signalling stimulation with Activin A for 3 and 6 hours (T3 and T6 respectively).
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| Overall design |
RNA-sequencing performed on two wt and two Arkadia -/- mouse embryonic stem cell lines treated with receptor kinase inhibitor (SB431542) or Activin A for 3 and 6 hours.
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| Contributor(s) |
Carthy J, Episkopou V |
| Citation missing |
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| |
| Submission date |
Aug 01, 2018 |
| Last update date |
Mar 19, 2019 |
| Contact name |
Vasso Episkopou |
| E-mail(s) |
vasso.episkopou@imperial.ac.uk
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| Organization name |
Imperial College London
|
| Department |
Brain Sciences
|
| Street address |
Du Cane Road
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| City |
London |
| ZIP/Postal code |
W120nn |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA483989 |
| SRA |
SRP155996 |
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