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Series GSE117846 Query DataSets for GSE117846
Status Public on Jul 01, 2021
Title Gefitinib treatment in human EGFR-driven-Gefitinib resistant tumoral cell line
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary In order to analyze the molecular effect of the combination of Notch inhibitors and EGFR inhibitors on resistance to TKI,
we performed RNA-seq gene expression profiling of PC9 resistant to Gefitinib cells treated with different combinations.
Overall design Cells were treated with each drug alone (DBZ for Notch inhibition or Gefitinib for EGFR inhibition) or a combination of both drugs.
Contributor(s) Maraver A, Colinge J, Bousquet E, Bernardo S
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Submission date Jul 30, 2018
Last update date Jul 01, 2021
Contact name Jacques Colinge
Organization name Inserm
Street address 208, avenue des Apothicaires
City Montpellier
ZIP/Postal code 34000
Country France
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (6)
GSM3310586 Control 1
GSM3310587 Control 2
GSM3310588 Control 3
BioProject PRJNA483409
SRA SRP155717

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE117846_normalized_counts_coding.txt.gz 480.7 Kb (ftp)(http) TXT
GSE117846_notch_counts_all.txt.gz 1.1 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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