|
| Status |
Public on Oct 17, 2018 |
| Title |
Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition [thyroid] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This study assessed tumor suppressor roles of CREBBP in SCLC and other neuroendocrine tumors. Genetically engineered mouse models were used to determine the tumor suppressor role of Crebbp in SCLC and other neuroendocrine tumors.
|
| |
|
| Overall design |
Identification of differentially expressed genes regulated by Crebbp using primary thyroid tumors derived from genetically engineered mouse model.
|
| |
|
| Contributor(s) |
MacPherson D, Jia D |
| Citation(s) |
30181244 |
| |
| Submission date |
Jul 23, 2018 |
| Last update date |
Mar 21, 2019 |
| Contact name |
David MacPherson |
| Organization name |
Fred Hutchinson Cancer Research Center
|
| Street address |
1100 Fairview Ave N
|
| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (12)
|
|
| This SubSeries is part of SuperSeries: |
| GSE117552 |
Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition |
|
| Relations |
| BioProject |
PRJNA482447 |
| SRA |
SRP154932 |
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