|
| Status |
Public on May 24, 2020 |
| Title |
Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report the generation of isogenic hPSC model of FXS and characterize the neurodevelopmental capacity of these cells, performed transcriptome profiling in FXS neurons and identified key pathways
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| |
|
| Overall design |
Transcriptome profiling of FXS-derived neurons from hESC generated by RNA-seq in four replicates per genotype for using Illumina HiSeq4000. Control and FXS-derived neurons from hiPSC were generated by RNA-seq in 3 replicates per genotype.
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| |
|
| Contributor(s) |
Pouladi MA, Utami KH |
| Citation(s) |
32653109 |
| |
| Submission date |
Jul 17, 2018 |
| Last update date |
Sep 08, 2020 |
| Contact name |
Kagistia Hana Utami |
| E-mail(s) |
kagistia_hana_utami@tlgm.a-star.edu.sg
|
| Phone |
+65 64074383
|
| Organization name |
Translational Laboratory in Genetic Medicine
|
| Street address |
8A Biomedical Grove
|
| City |
Singapore |
| ZIP/Postal code |
138648 |
| Country |
Singapore |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (24)
|
|
| Relations |
| BioProject |
PRJNA481532 |
| SRA |
SRP154204 |
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