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Series GSE116637 Query DataSets for GSE116637
Status Public on Jul 06, 2018
Title RNA-seq of eight lymphoblastoid cell lines after AHR ligand treatments
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RNA-seq was done on eight different lymphoblastoid cell lines for vehicle control, 3-MC agonist treatment and GNF-351 antagonist treatment for AHR to look at AHR regulated genes with different genetic backgrounds. We identified 69 genes that were highly differentially expressed after 3-MC or GNF-351 antagonist treatment with variation in the degree fo differential expression between the eight cell lines.
 
Overall design Eight lymphoblastoid cells lines were treated in duplicate with vehicle control, 3-MC or GNF-351 for 24 hours before RNA collection. Libraries were prepared on the TruSeq RNA Library Prep Kit v2 and paired end sequencing was carried out on Illumina HiSeq 4000
 
Contributor(s) Weinshlboum RM, Neavin DR, Wang L
Citation(s) 31292129
Submission date Jul 05, 2018
Last update date May 12, 2020
Contact name Drew Neavin
E-mail(s) d.neavin@garvan.org.au
Organization name Garvan Institute of Medical Research
Department Cellular Science
Street address 384 Victoria St
City Darlinghurst
State/province New South Wales
ZIP/Postal code 2010
Country Australia
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (48)
GSM3244545 CA12_3MC_1 (rna-seq)
GSM3244546 CA12_3MC_2 (rna-seq)
GSM3244547 CA12_DMSO_1 (rna-seq)
This SubSeries is part of SuperSeries:
GSE116638 Role of AHR in lymphoblastoid cell lines
Relations
BioProject PRJNA479764
SRA SRP152203

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE116637_counts.txt.gz 3.9 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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