|
| Status |
Public on Dec 19, 2018 |
| Title |
Genetic models reveal cis and trans immune-regulatory activities for lincRNA-Cox2 in vivo (lungs and spleens) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Here we compare gene expression profiles between lungs and spleens following LPS in vivo injection into Wild type, lincRNA-Cox2 knockout and lincRNA-Cox2 mutant mice
The aim of the experiment is to determine the cis and trans functions for lincRNA-Cox2 following in vivo LPS challenge within the spleen and lung
|
| |
|
| Overall design |
Lungs and spleens were extracted from 8 week old wild type, lincRNA-Cox2 knockout and mutant mice following 6h of LPS treatment (20mg/kg) and placed directly in Trizol. RNA was isolated and sequenced
|
| |
|
| Contributor(s) |
Carpenter S |
| Citation(s) |
30404006, 35365562 |
| |
| Submission date |
Jun 27, 2018 |
| Last update date |
May 05, 2022 |
| Contact name |
Susan Carpenter |
| E-mail(s) |
sucarpen@ucsc.edu
|
| Phone |
8315028155
|
| Organization name |
University of California Santa Cruz
|
| Department |
Molecular Cell and Developmental Biology
|
| Lab |
Carpenter Lab
|
| Street address |
1156 High Street
|
| City |
Santa Cruz |
| State/province |
CA |
| ZIP/Postal code |
95064 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (30)
|
|
| This SubSeries is part of SuperSeries: |
| GSE117379 |
Genetic models reveal cis and trans immune-regulatory activities for lincRNA-Cox2 in vivo |
|
| Relations |
| BioProject |
PRJNA478239 |
| SRA |
SRP151481 |
Less...
More...