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Status |
Public on Sep 01, 2019 |
Title |
Protein arginine methyltransferase PRMT1 is essential for palatogenesis |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
We report that neural crest-specific deletion of Prmt1 caused craniofacial malformations including cleft palate.
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Overall design |
It is expected that genes involved in proliferation and cell cycle control are altered by Prmt1 deficiency.
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Contributor(s) |
Gou Y, Li J, Jackson-Weaver O, Wu J, Zhang T, Zhang T, Higuchi Y, Cho I, Ho T, Chen Y, Li M, Richard S, Wang J, Chai Y, Xu J |
Citation missing |
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Submission date |
May 24, 2018 |
Last update date |
Sep 01, 2019 |
Contact name |
Jian Xu |
Organization name |
University of Southern California
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Department |
Center for Craniofacial Molecular Biology
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Street address |
2250 Alcazar Street, CSA 106
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City |
Los Angeles |
State/province |
CA |
ZIP/Postal code |
90033 |
Country |
USA |
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Platforms (1) |
GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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Samples (6)
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Relations |
BioProject |
PRJNA472987 |
SRA |
SRP148899 |