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| Status |
Public on Dec 26, 2018 |
| Title |
Gene expression data from HepG2 SND1 knockdown stable cell lines after 5-Fu treatment |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
SND1 protein is a highly conserved protein of eukaryotic cells and is involved in a group of cellular biological processes, such as gene transcription, pre-mRNA splicing, cell cycle, DNA damage repair, proliferation and programmed cell death degradome, adipogenesis and cancerogenesis. SND1 can promote the metastasis and proliferation of breast cancer cells by down-regulating the miR-127 expression.
Herein, we used microarrays to detail the potential molecular mechanism in the chemotherapy drug-induced HCC apoptosis.
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| Overall design |
HepG2 stable cell lines of shSND1-#1 and pLKO-Vector were treated with 6μg/mL 5-Fu, respectively. 48 h after treatment, total RNA was extracted. cDNA was synthesized and hybridised to Affymetrix microarrays.
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| Contributor(s) |
Cui X, Gao X, Yang J |
| Citation(s) |
30321081, 34608846 |
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| Submission date |
May 15, 2018 |
| Last update date |
Feb 08, 2022 |
| Contact name |
Xiaoteng Cui |
| Organization name |
Tianjin Medical University
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| Street address |
NO. 22, Qixiangtai Road, Heping district
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| City |
Tianjin |
| ZIP/Postal code |
300070 |
| Country |
China |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA471413 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE114447_RAW.tar |
134.7 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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