|
| Status |
Public on Aug 30, 2018 |
| Title |
Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To confirm the effect of estrogen, through the estrogen receptor, on cell cycle progression and to identify the key molecules that play an important role in this regulation, MCF-7aro (ER+ cell line) and C4-12ERaERE (ER lacking cell line stably transfected with ERaERE) were used for RNAseq analysis. Processed data includes new data for C4-12 samples as well as re-processed data from SRP035276.
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| |
|
| Overall design |
6 new C4-12 samples were analyzed (3 control and 3 E2 treated). Same design as for subset of MCF7aro SRP035276 re-processed samples, in addition to Paroxetine and Paroxetine+E2 treatments.
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| |
|
| Contributor(s) |
Petrossian K, Kanaya N, Chen S |
| Citation(s) |
29963233 |
| |
| Submission date |
May 09, 2018 |
| Last update date |
Apr 23, 2020 |
| Contact name |
Karineh Petrossian |
| E-mail(s) |
kpetrossianphd@gmail.com
|
| Organization name |
Beckman Research Institute at City of Hope
|
| Department |
Cancer Biology
|
| Lab |
KCRB 2018
|
| Street address |
1500 E. Duarte Road
|
| City |
Duarte |
| State/province |
CA |
| ZIP/Postal code |
91010 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (18)
|
|
| Relations |
| BioProject |
PRJNA470688 |
| SRA |
SRP145128 |
| SRA |
SRP035276 |
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