|
| Status |
Public on Jun 08, 2018 |
| Title |
Total and GC B cells with or without miR-146a |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To examine the impact of miR-146a on GC B cell development, transcriptomic profilings of total B cells isolated from unimmunized mice with B cell-specific deletion of miR-146a (B-KO) or GC B cells isolated from B-KO mice upon sheep red blood cell (SRBC) immunization were done.
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| |
|
| Overall design |
B cells or GC B cells isolated from mice with B cell-specific deletion of miR-146a with or without SRBC immunization
|
| |
|
| Contributor(s) |
Cho S, Lee H, Yu I, Choi YS, Huang H, Hashemifar SS, Lin L, Chen M, Afanasiev ND, Khan AA, Lin S, Rudensky AY, Crotty S, Lu L |
| Citation(s) |
30013024 |
| |
| Submission date |
May 02, 2018 |
| Last update date |
Nov 22, 2021 |
| Contact name |
Li-Fan Lu |
| E-mail(s) |
lifanlu@ucsd.edu
|
| Organization name |
University of California, San Diego
|
| Department |
Biological Sciences
|
| Street address |
9500 Gilman Dr., NSB 5314
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92093 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (12)
|
| GSM3127222 |
B_WT_nonimm_1: non-immunized WT B cells |
| GSM3127223 |
B_WT_nonimm_2: non-immunized WT B cells |
| GSM3127224 |
B_WT_nonimm_3: non-immunized WT B cells |
| GSM3127225 |
GCB_WT_SRBC_1: SRBC-immunized WT GC B cells |
| GSM3127226 |
GCB_WT_SRBC_2: SRBC-immunized WT GC B cells |
| GSM3127227 |
GCB_WT_SRBC_3: SRBC-immunized WT GC B cells |
| GSM3127228 |
B_KO_nonimm_1: non-immunized miR-146a KO B cells |
| GSM3127229 |
B_KO_nonimm_2: non-immunized miR-146a KO B cells |
| GSM3127230 |
B_KO_nonimm_3: non-immunized miR-146a KO B cells |
| GSM3127231 |
GCB_KO_SRBC_1: SRBC-immunized miR-146a KO GC B cells |
| GSM3127232 |
GCB_KO_SRBC_2: SRBC-immunized miR-146a KO GC B cells |
| GSM3127233 |
GCB_KO_SRBC_3: SRBC-immunized miR-146a KO GC B cells |
|
| Relations |
| BioProject |
PRJNA454714 |
| SRA |
SRP144378 |
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