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| Status |
Public on Dec 26, 2018 |
| Title |
Diethyldithiocarbamate, an anti-abuse drug, alleviates steatohepatitis and fibrosis in rodents |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
C57BL/6 mice received methionine/choline deficient (MCD) diet to establish the model of non-alcoholic fatty liver disease (NAFLD) with or without Diethyldithiocarbamate (DDC) treatment.
DDC improves hepatic steatosis, ballooning, inflammation and fibrosis in rodent models of NAFLD through modulating lipid metabolism and oxidative stress.
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| Overall design |
In this study, mRNA in liver tissues from 2 normal control mice, 3 MCD-induced mice and 3 MCD-induced mice with DDC treatment were analyzed by microarray.
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| Contributor(s) |
Liu T |
| Citation(s) |
30266038 |
| |
| Submission date |
Apr 30, 2018 |
| Last update date |
Dec 26, 2018 |
| Contact name |
Tianhui Liu |
| E-mail(s) |
liu_tianhui@163.com
|
| Organization name |
Beijing Friendship Hospital, Capital Medical University
|
| Street address |
No. 95 Yong-an Road, Xi-cheng District
|
| City |
Beijing |
| ZIP/Postal code |
100050 |
| Country |
China |
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| Platforms (1) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA454221 |
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