|
| Status |
Public on Dec 25, 2018 |
| Title |
Medial prefrontal cortex (mPFC) transcriptome analysis of Shank3-overexpressing mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Shank3 is a core excitatory postsynaptic protein expressed in multiple brain regions including the medial prefrontal cortex, striatum, and hippocampus. We have previously generated and characterized Shank3-overexpressing transgenic mice, and found that these mice exhibited manic-like behavioral phenotypes. To understand molecular mechanisms underlying the behavioral changes, we performed transcriptome (RNA-sequencing) analysis of the mPFC tissues from 10 to 12-week-old wild-type and Shank3 transgenic mice.
|
| |
|
| Overall design |
Medial prefrontal cortex (mPFC) transcriptome of 10 to 12-week-old wild-type and Shank3 transgenic (TG) mice.
|
| |
|
| Contributor(s) |
Han K, Chunmei J, Kang H |
| Citation(s) |
30233305 |
| |
| Submission date |
Apr 19, 2018 |
| Last update date |
Mar 19, 2019 |
| Contact name |
Kihoon Han |
| E-mail(s) |
neurohan@korea.ac.kr
|
| Organization name |
Korea University College of Medicine
|
| Department |
Neuroscience
|
| Street address |
73, Inchon-ro, Seongbuk-gu
|
| City |
Seoul |
| ZIP/Postal code |
02841 |
| Country |
South Korea |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA450933 |
| SRA |
SRP141125 |
Less...
More...