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| Status |
Public on Jun 23, 2019 |
| Title |
H3K27ac, H3K4me and H3K4me3 binding examined by ChIP-seq in the CHP-134 neuroblastoma cell line |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Super-enhancers are defined by peaks in H3K27 acetylation and H3K4 mono-methylation, and the lack of H3K4 tri-methylation. They have been found to play a role in oncogene transcription and tumour maintenance.
Using ChIP-Seq, we profiled H3K27ac, H3K4me and H3K4me3 binding in CHP-134 neuroblastoma cells.
We identified H3K27ac, H3K4me and H3K4me3 binding sites in the CHP-134 neuroblastoma cell line.
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| |
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| Overall design |
Identification of potential enhancer and super-enhancer sites in the CHP-134 neuroblastoma cell line.
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| |
|
| Contributor(s) |
Liu T, Wong M, Poulos R |
| Citation(s) |
31346162 |
| |
| Submission date |
Apr 13, 2018 |
| Last update date |
Sep 23, 2019 |
| Contact name |
matthew kwok kei wong |
| E-mail(s) |
MWong@ccia.org.au
|
| Organization name |
Children's Cancer Institute
|
| Department |
histone modification group
|
| Street address |
Lowy cancer centre, University of New South Wales
|
| City |
Sydney |
| State/province |
New South Wales |
| ZIP/Postal code |
2031 |
| Country |
Australia |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (5)
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| This SubSeries is part of SuperSeries: |
| GSE113140 |
JMJD6 gene gain is a tumorigenic factor and therapeutic target in neuroblastoma |
|
| Relations |
| BioProject |
PRJNA450134 |
| SRA |
SRP139966 |
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