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Series GSE112892 Query DataSets for GSE112892
Status Public on Jan 01, 2023
Title RNA-seq analysis about MuERVL knocked down samples
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Endogenous retrovirus MERVL is specifically expressed in a minority of embryonic stem cells and 2-cell embryos. To determine the function of MERVL transcripts, we knocked down MuERVL and analyzed the effect on the expression of MERVL and its targeting genes. It turns out the downregulation of MuERVL would lead to downregulation of MERVL nearby genes. This study extends our understandings of the machanism by which MERVL regulates its neatby genes.
Overall design We knocked down MuERVL in E14 by shRNA. We performed RNA-seq analysis in order to exam the transcriptome after MuERVL knockdown.
Contributor(s) Zhang W, Chen R
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Submission date Apr 09, 2018
Last update date Jan 01, 2023
Contact name Weiyu Zhang
Phone 18902012072
Organization name Nankai University
Street address No.38 Tongyan Road, Jinnan District
City Tainjin
ZIP/Postal code 300350
Country China
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (4)
GSM3090519 KD_random rep1
GSM3090520 KD_random rep2
GSM3090521 KD_MERVL rep1
BioProject PRJNA449389

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE112892_Normalized_counts.txt.gz 167.8 Kb (ftp)(http) TXT
GSE112892_raw_counts.txt.gz 326.6 Kb (ftp)(http) TXT
Raw data are available in SRA
Processed data are available on Series record

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