|
| Status |
Public on Jan 01, 2023 |
| Title |
RNA-seq analysis about MuERVL knocked down samples |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Endogenous retrovirus MERVL is specifically expressed in a minority of embryonic stem cells and 2-cell embryos. To determine the function of MERVL transcripts, we knocked down MuERVL and analyzed the effect on the expression of MERVL and its targeting genes. It turns out the downregulation of MuERVL would lead to downregulation of MERVL nearby genes. This study extends our understandings of the machanism by which MERVL regulates its neatby genes.
|
| |
|
| Overall design |
We knocked down MuERVL in E14 by shRNA. We performed RNA-seq analysis in order to exam the transcriptome after MuERVL knockdown.
|
| |
|
| Contributor(s) |
Zhang W, Chen R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 09, 2018 |
| Last update date |
Jan 01, 2023 |
| Contact name |
Weiyu Zhang |
| E-mail(s) |
ch8316f5eyu@gmail.com
|
| Phone |
18902012072
|
| Organization name |
Nankai University
|
| Street address |
No.38 Tongyan Road, Jinnan District
|
| City |
Tainjin |
| ZIP/Postal code |
300350 |
| Country |
China |
| |
|
| Platforms (1) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA449389 |
Less...
More...