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Status |
Public on Oct 01, 2018 |
Title |
A Kelch domain-containing KLHDC7B and a long non-coding RNA ST8SIA6-AS1 act oppositely on breast cancer cell proliferation via the interferon signaling pathway (KLHDC7B knockdown) |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Kelch domain-containing 7B (KLHDC7B) was revealed hypermethylated at promoter but upregulated in breast cancer. And we identified a long non-coding RNA, ST8SIA6-AS1 (STAR1), of which expression was highly associated with KLHDC7B in breast cancer (r = 0.5887).
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Overall design |
Control sample is transfected RNA using si negative control and Test sample is a knockdown using KLHDC7B's siRNA. Both sample RNA is extracted from breast cancer cell MCF-7
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Contributor(s) |
Jeong G, Bae H, Kim SJ |
Citation(s) |
30150751 |
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Submission date |
Mar 30, 2018 |
Last update date |
Dec 21, 2018 |
Contact name |
Juyeon Ham |
E-mail(s) |
wndus1000@naver.com
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Organization name |
Dongguk University
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Street address |
32, Dongguk-ro
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City |
Ilsan |
ZIP/Postal code |
10326 |
Country |
South Korea |
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Platforms (1) |
GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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Samples (2) |
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This SubSeries is part of SuperSeries: |
GSE112587 |
A Kelch domain-containing KLHDC7B and a long non-coding RNA ST8SIA6-AS1 act oppositely on breast cancer cell proliferation via the interferon signaling pathway |
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Relations |
BioProject |
PRJNA448060 |