|
| Status |
Public on Jan 09, 2019 |
| Title |
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2 [RNA-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We performed RNA-seq to identify differentially expressed genes in response to knockout of EZH2 and global miRNA knockdown (VP55 overexpressed) in T98G Glioblastoma multiforme cells.
|
| |
|
| Overall design |
RNA-seq in WT and EZH2-/- T98G cells and VP55 overexpressed WT and EZH2-/- T98G cells.
|
| |
|
| Contributor(s) |
Shivram H, Iyer V |
| Citation(s) |
30651280 |
| |
| Submission date |
Mar 22, 2018 |
| Last update date |
Apr 10, 2019 |
| Contact name |
Vishy Iyer |
| E-mail(s) |
iyerlab@gmail.com
|
| Phone |
5122327833
|
| Organization name |
University of Texas at Austin
|
| Department |
Molecular Biosciences
|
| Street address |
2500 Speedway Dr. MBB 3.212
|
| City |
Austin |
| State/province |
TX |
| ZIP/Postal code |
78712 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (12)
|
| GSM3061517 |
EZH2-/- - Dox (VP55 overexpression) replicate 1 |
| GSM3061518 |
WT - Dox (VP55 overexpression) replicate 1 |
| GSM3061519 |
EZH2-/- + Dox (VP55 overexpression) replicate 1 |
|
| This SubSeries is part of SuperSeries: |
| GSE112242 |
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network |
|
| Relations |
| BioProject |
PRJNA445338 |
| SRA |
SRP136292 |
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