Expression profiling by high throughput sequencing
Summary
We performed RNA sequencing in different wildtype and E47ko tissues in response to treatment with glucocorticoids. We show a global deregulation of gene expression programs involved in lipid, triglyceride and cholesterol metabolism & transport for E47 mutant liver tissue.
Overall design
mRNA profiles of different wildtype and E47ko tissues in response to long-term and short-term treatment with glucocorticoids (Dex, Cort).
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