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| Status |
Public on Mar 06, 2019 |
| Title |
RNA-seq of MLLT3-overexpressing cultued HSPC, compared to non-overexpressing and uncutured FL-HSPC [RNAseq_MLLT3_OE] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
MLLT3 preserves the FL-HSPC gene expression signature in culture
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| Overall design |
FL-HSPC were infected with Control or MLLT3-OE lentivirus and cultured for 4 weeks on OP9M2. sorted HSPC were profiled before (n=3) or after (n=6) culture
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| Contributor(s) |
Calvanese V, Nguyen AT, Bolan TJ, Wang Y, Lay FD, Magnusson M, Kurdistani SK, Mikkola HK |
| Citation(s) |
31776511 |
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| Submission date |
Mar 06, 2018 |
| Last update date |
Dec 28, 2023 |
| Contact name |
Vincenzo Calvanese |
| E-mail(s) |
vincalv@gmail.com
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| Organization name |
UCLA
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| Street address |
615 Charles E Young Dr S
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| City |
Los Angeles |
| ZIP/Postal code |
90095 |
| Country |
USA |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (15)
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| GSM3032105 |
Fetal liver HSPC,infected with CTR FUGW vector sample1 |
| GSM3032106 |
Fetal liver HSPC,infected with CTR FUGW vector sample2 |
| GSM3032107 |
Fetal liver HSPC,infected with CTR FUGW vector sample3 |
| GSM3032108 |
Fetal liver HSPC,infected with CTR FUGW vector sample4 |
| GSM3032109 |
Fetal liver HSPC,infected with CTR FUGW vector sample5 |
| GSM3032110 |
Fetal liver HSPC,infected with CTR FUGW vector sample6 |
| GSM3032111 |
Fetal liver HSPC,infected with MLLT3-OE vector sample1 |
| GSM3032112 |
Fetal liver HSPC,infected with MLLT3-OE vector sample2 |
| GSM3032113 |
Fetal liver HSPC,infected with MLLT3-OE vector sample3 |
| GSM3032114 |
Fetal liver HSPC,infected with MLLT3-OE vector sample4 |
| GSM3032115 |
Fetal liver HSPC,infected with MLLT3-OE vector sample5 |
| GSM3032116 |
Fetal liver HSPC,infected with MLLT3-OE vector sample6 |
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| This SubSeries is part of SuperSeries: |
| GSE111484 |
Mllt3 Governs Self-Renewal And Engraftment Of Human Hematopoietic Stem Cells |
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| Relations |
| BioProject |
PRJNA437152 |
| SRA |
SRP134043 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE111483_MLLT3OE4w_6s_d0_3s_exoRpkmSt.txt.gz |
1.7 Mb |
(ftp)(http) |
TXT |
| GSE111483_diffOE4w_6s_paired_edgeR.txt.gz |
2.1 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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