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| Status |
Public on Apr 05, 2018 |
| Title |
Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration: part II |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We identified that microRNA-150 is upregulated in aged macrophages of diverse origins and therefore may mechanistically skew them towards a disease-promoting phenotype. The purpose of this experiment was to identify how the murine transcriptome changes with microRNA-150 overexpression.
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| Overall design |
We prepared 12 samples (N=6/group; microRNA-150_overexpression versus negative control). Quality control revealed improper fragmentation of one sample, which we omitted from further analysis. This sample has not been included in these records.
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| |
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| Contributor(s) |
Lin JB |
| Citation(s) |
29618664 |
| |
| Submission date |
Mar 01, 2018 |
| Last update date |
Mar 21, 2019 |
| Contact name |
Jonathan Lin |
| E-mail(s) |
jblin6@gmail.com
|
| Organization name |
Washington University School of Medicine
|
| Street address |
660 S. Euclid Ave, Campus Box 8096
|
| City |
Saint Louis |
| State/province |
MO |
| ZIP/Postal code |
63110 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (11)
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| This SubSeries is part of SuperSeries: |
| GSE111323 |
Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration |
|
| Relations |
| BioProject |
PRJNA436592 |
| SRA |
SRP133788 |
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