|
| Status |
Public on Dec 05, 2018 |
| Title |
NSD2 is a conserved driver of metastatic prostate cancer progression. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Analysis of transcriptome of FACS isolated cancer cells from prostate primary tumors and metastasis from NPK GEM models
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| Overall design |
Prostate tissue or tumor from pre-metastatic; post-metastatic; and lung, liver and lymph node metastasis from Nkx3.1CreERT2/+ ;Ptenflox/flox;KrasLSL-G12D/+ mice was harvested, and snap frozen for subsequent molecular analysis. Tumors had been induced by tamoxifen (100mg/kg oral gavage) induced recombination at 2 months of age.
Total RNA obtained from prostate tissues or tumors. Prostate tissues or tumors were harvested and processed for RNA isolation and transcriptome analysis using the MagMAX RNA isolation kit (Ambion).
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| |
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| Contributor(s) |
Aytes A, Mitrofanova A, Giacobe A, Abate-Shen C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Mar 01, 2018 |
| Last update date |
Mar 20, 2021 |
| Contact name |
Alvaro Aytes |
| E-mail(s) |
aaytes@idibell.cat
|
| Phone |
+34932607464
|
| Organization name |
IDIBELL
|
| Department |
ProCURE
|
| Lab |
Prostate Lab
|
| Street address |
Granvia 199
|
| City |
Hospitalet de Llobregat |
| State/province |
Catalonia |
| ZIP/Postal code |
08907 |
| Country |
Spain |
| |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (39)
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| This SubSeries is part of SuperSeries: |
| GSE118936 |
NSD2 is an actionable driver of prostate cancer metastasis |
|
| Relations |
| BioProject |
PRJNA436465 |
| SRA |
SRP133734 |
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