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Status |
Public on Feb 21, 2020 |
Title |
Transcriptomes of Hemin exposed trained monocytes |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Innate immune memory is the phenomenon whereby innate immune cells such as monocytes or macrophages undergo functional reprogramming after exposure to microbial components. In this study we apply RNA-seq analysis to healthy human monocytes exposed to Hemin, a danger-associated signal, and B-glucan, a yeast sugar, in vitro.
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Overall design |
Monocytes from healthy donors were cultured in vitro for 24 hours with media, Hemin or B-glucan.
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Contributor(s) |
Jentho E, Novakovic B, Weis S |
Citation missing |
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Submission date |
Feb 21, 2018 |
Last update date |
Feb 23, 2020 |
Contact name |
Cristian Ruiz-Moreno |
E-mail(s) |
c.c.ruizmoreno@prinsesmaximacentrum.nl
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Organization name |
Prinses Máxima Centrum
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Street address |
25 Heidelberglaan
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City |
Utrecht |
State/province |
Utrecht |
ZIP/Postal code |
3584 CS |
Country |
Netherlands |
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Platforms (1) |
GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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Samples (70)
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This SubSeries is part of SuperSeries: |
GSE111003 |
Transcriptomes and Epigenomes of Hemin exposed trained monocytes |
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Relations |
BioProject |
PRJNA435107 |
SRA |
SRP133223 |