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| Status |
Public on Jan 02, 2019 |
| Title |
Comparison between nitroglycerine and vehicle treatments in mouse trigeminal ganglia and nucleus accumbens |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Chronic nitroglycerin treatment elicits hyperalgesia in mice that is significantly augmented by a human migraine trigger and reduced with migraine therapy. The purpose of this study was to profile mRNA levels (transcriptome) to understand the differences between nitroglicerin and vehicle treatments in two nervous system regions, the trigeminal ganglia and the nucleus accumbens,
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| Overall design |
RNA samples were obtained from 10 mice 24 hours after the last nitroglicerin injection (Intraperitoneal injections of nitroglycerin every second day for 9 days total) and were subjected to paired-end RNA sequencing
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| Contributor(s) |
Rodriguez Zas S |
| Citation(s) |
30618656, 35047432 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| P30 DA018310 |
BIOINFORMATICS CORE |
UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN |
SANDRA L RODRIGUEZ ZAS |
| R21 DA027548 |
Integration of resources and studies to elucidate neuropeptide signaling |
UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN |
SANDRA L RODRIGUEZ ZAS |
| R21 MH096030 |
Inflammation-Induced Behavioral Alterations: A Psychogenomic Approach |
UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN |
SANDRA L RODRIGUEZ ZAS |
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| |
| Submission date |
Feb 06, 2018 |
| Last update date |
Jan 31, 2022 |
| Contact name |
Sandra Rodriguez Zas |
| Organization name |
University of Illinois at Urbana
|
| Street address |
1207 W. Gregory Dr.
|
| City |
Urbana |
| State/province |
IL - Illinois |
| ZIP/Postal code |
61801 |
| Country |
USA |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA433105 |
| SRA |
SRP132264 |
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