|
| Status |
Public on Jul 08, 2019 |
| Title |
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-Sequencing Analysis of gene expression changes due to ablation of Ets1 in SCC25 Cells.
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| |
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| Overall design |
Global transcriptomic characterization of the effects of Ets1 knockdown in SCC25 Head and Neck Squamous Cell Carcinoma cells was performed via RNA-Seq Analysis. The knockdown of ETS1 was performed using transient siRNA based approach as well as stable cell lines were generated with targeted shRNA. As controls, we used SCC25 cells transduced with siRNAs and shRNAs with non-silencing control hairpin sequences that do not match any known mammalian genes and hence are not expected to not target any gene product.
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| |
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| Contributor(s) |
Gluck C, Sethi I, Sinha S |
| Citation(s) |
31306413 |
| |
| Submission date |
Jan 30, 2018 |
| Last update date |
Oct 07, 2019 |
| Contact name |
Satrajit Sinha |
| E-mail(s) |
ssinha2@buffalo.edu
|
| Phone |
716-881-7994
|
| Organization name |
State University of New York at Buffalo
|
| Department |
Department of Biochemistry
|
| Street address |
701 Ellicott Street
|
| City |
Buffalo |
| State/province |
NY |
| ZIP/Postal code |
14203 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE109896 |
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma |
|
| Relations |
| BioProject |
PRJNA432253 |
| SRA |
SRP131807 |
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