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Series GSE109844 Query DataSets for GSE109844
Status Public on Nov 14, 2018
Title The expression profiles of CD4low(HLA-G+) T cells
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The aim of the dataset was to demonstrate that CD4low T cells were murine homolog of CD4lowHLA-G+ T cells by comparing the expression profiles of CD4lowHLA-G+ T cells in prostate cancer (PCa) patients to those of CD4low T cells in PCa mouse models.
Overall design mRNA profiles of CD4lowHLA-G+ T cells isolated from PCa patients with androgen deprivation therapy (ADT) and naïve CD4+ T cells derived from healthy donors (HD) as controls were generated by deep sequencing, in duplicate, using Illumina HiSeq X Tten. mRNA of CD4low T cells isolated from castrated TRAMP mice and naive CD4+ T cells derived from wild-type mice as controls were sequenced, in duplicate,using Illumina HiSeq X Tten.To determine whether CD4low T cells were murine homolog of CD4lowHLA-G+ T cells,the expression profiles of CD4lowHLA-G+ T cells and CD4low T cells were compared.
Contributor(s) Wang C, Zhang Y, Gao WQ
Citation(s) 30297869
Submission date Jan 30, 2018
Last update date Mar 20, 2019
Contact name Chao Wang
Organization name Shanghai Jiao Tong University
Street address 1954HuaShan road
City ShangHai
ZIP/Postal code 200030
Country China
Platforms (2)
GPL20795 HiSeq X Ten (Homo sapiens)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (8)
GSM2971197 human naïve CD4 rep1
GSM2971198 human naïve CD4 rep2
GSM2971199 CD4lowHLA-G+ T cells rep1
BioProject PRJNA432170
SRA SRP131776

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Supplementary file Size Download File type/resource
GSE109844_CD4lowHLA-G_vs_human_N_CD4.xls.gz 780.6 Kb (ftp)(http) XLS
GSE109844_CD4lowHLA-G_vs_human_N_CD4_diff.xls.gz 1.5 Mb (ftp)(http) XLS
GSE109844_CD4low_vs_murine_N_CD4.xls.gz 699.3 Kb (ftp)(http) XLS
GSE109844_CD4low_vs_murine_N_CD4_diff.xls.gz 1.2 Mb (ftp)(http) XLS
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