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| Status |
Public on Nov 14, 2018 |
| Title |
The expression profiles of CD4low(HLA-G+) T cells |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The aim of the dataset was to demonstrate that CD4low T cells were murine homolog of CD4lowHLA-G+ T cells by comparing the expression profiles of CD4lowHLA-G+ T cells in prostate cancer (PCa) patients to those of CD4low T cells in PCa mouse models.
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| Overall design |
mRNA profiles of CD4lowHLA-G+ T cells isolated from PCa patients with androgen deprivation therapy (ADT) and naïve CD4+ T cells derived from healthy donors (HD) as controls were generated by deep sequencing, in duplicate, using Illumina HiSeq X Tten. mRNA of CD4low T cells isolated from castrated TRAMP mice and naive CD4+ T cells derived from wild-type mice as controls were sequenced, in duplicate,using Illumina HiSeq X Tten.To determine whether CD4low T cells were murine homolog of CD4lowHLA-G+ T cells,the expression profiles of CD4lowHLA-G+ T cells and CD4low T cells were compared.
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| Contributor(s) |
Wang C, Zhang Y, Gao WQ |
| Citation(s) |
30297869 |
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| Submission date |
Jan 30, 2018 |
| Last update date |
Mar 20, 2019 |
| Contact name |
Chao Wang |
| E-mail(s) |
tedwang@sjtu.edu.cn
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| Organization name |
Shanghai Jiao Tong University
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| Street address |
1954HuaShan road
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| City |
ShangHai |
| ZIP/Postal code |
200030 |
| Country |
China |
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| Platforms (2) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA432170 |
| SRA |
SRP131776 |
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