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Series GSE108854 Query DataSets for GSE108854
Status Public on Jan 08, 2019
Title Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Gene expression profiles from ALDH high cells sorted from expanded adult human pancreatic organoids are more similar to fetal pancreatic tissue and ALDH high cells sorted from expanded fetal human pancreatic organoids than to adult human islets or adult islet-depleted exocrine tissue.
 
Overall design RNA was isolated from ALDHhi cells sorted from organoids after 7 days expansion derived from human adult pancreatic tissue, ALDHhi cells sorted from organoids after 7 days expansion derived from human fetal pancreatic tissue, primary fetal pancreatic tissue, adult human islets from different donors and adult exocrine (islet-depleted) pancreatic tissue from different donors.
 
Contributor(s) Willams N, Kester L, de Koning E, van Oudenaarden A, Loomans C
Citation(s) 29539434
Submission date Jan 08, 2018
Last update date Jul 29, 2019
Contact name Eelco de Koning
E-mail(s) e.dekoning@lumc.nl
Phone +31 6 46112966
Organization name LUMC
Department Medicine
Street address Albinusdreef 2
City Leiden
ZIP/Postal code 2333 ZA
Country Netherlands
 
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (18)
GSM2915020 A1: Extracted RNA from ALDH high cells from 7-day expanded adult pancreatic organoids
GSM2915021 A2: Extracted RNA from ALDH high cells from 7-day expanded adult pancreatic organoids
GSM2915022 A3: Extracted RNA from ALDH high cells from 7-day expanded adult pancreatic organoids
Relations
BioProject PRJNA428952
SRA SRP128458

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE108854_pan_counttable_def.xlsx 3.0 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record
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