|
| Status |
Public on Feb 21, 2018 |
| Title |
Transcriptional profiles of lung macrophage subsets in Mycobacterium Tuberculosis infection |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We investigated transcriptional responses of different lung macrophage lineages during M.tuberculosis infection by RNAseq. Our data revealed that different lineages of macrophages respond differentially to M.Tuberculosis infection.
|
| |
|
| Overall design |
Alveolar macrophage (AM) and interstitial macrophages (IM) with or without Mtb were FACS-sorted from Mtb infected mice for RNAseq.
|
| |
|
| Contributor(s) |
Huang L, Grenier JK, Russell DG |
| Citation(s) |
29500179 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 AI134183 |
A mechanistic understanding of tuberculosis progression through bacterial reporter strains |
Cornell University |
DAVID G RUSSELL |
|
| |
| Submission date |
Jan 08, 2018 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Lu Huang |
| E-mail(s) |
lh346@cornell.edu
|
| Organization name |
Cornell University
|
| Department |
Microbiology and Immunology
|
| Street address |
VMC C5-103
|
| City |
Ithaca |
| State/province |
NY |
| ZIP/Postal code |
14850 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA428925 |
| SRA |
SRP130944 |
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