|
| Status |
Public on Apr 10, 2019 |
| Title |
Regulation of hypoxia-inducible factor activity by ZMYND8 |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
|
| Summary |
ZMYND8 coactivates the global HIF target genes in breast cancer MDA-MB-231 cells.
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| |
|
| Overall design |
MDA-MB-231 cells were exposed to 20% or 1% O2 for 24 hrs and subjected to mRNA-seq. MDA-MB-231 cells were exposed to 1% O2 for 24 hrs and subjected to ChIP-seq.
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| |
|
| Contributor(s) |
Chen Y, Luo W |
| Citation(s) |
29629903 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R00 CA168746 |
The role of JMJD2C in HIF-1 activation and breast cancer progression |
UT SOUTHWESTERN MEDICAL CENTER |
Weibo Luo |
| R00 NS078049 |
The role of a novel AIF-associated nuclease PAAN1 in neuronal injury |
UT SOUTHWESTERN MEDICAL CENTER |
Yingfei Wang |
| R35 GM124693 |
PARP-1 Signaling in DNA Damage and Cell Death |
UT SOUTHWESTERN MEDICAL CENTER |
Yingfei Wang |
|
| |
| Submission date |
Jan 05, 2018 |
| Last update date |
Apr 14, 2019 |
| Contact name |
Weibo Luo |
| E-mail(s) |
weibo.luo@utsouthwestern.edu
|
| Phone |
214-645-4770
|
| Organization name |
UT Southwestern Medical Center
|
| Department |
Pathology
|
| Street address |
5323 Harry Hines Blvd.
|
| City |
Dallas |
| State/province |
Texas |
| ZIP/Postal code |
75390-9072 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (20)
|
|
| Relations |
| BioProject |
PRJNA428761 |
| SRA |
SRP130942 |
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