|
| Status |
Public on Mar 12, 2018 |
| Title |
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To elucidate whether RNF6 plays a role in colorectal cancer tumorigenesis, a RNA-seq analysis was performed to compare the gene expression profiles of RNF6 siRNA and control siRNA transfectants.
|
| |
|
| Overall design |
RNA-seq was performed in HT29 colorectal cancer cells after RNF6 knock down
|
| |
|
| Contributor(s) |
Chen H, Hong J |
| Citation(s) |
29288235 |
| |
| Submission date |
Dec 12, 2017 |
| Last update date |
Mar 27, 2019 |
| Contact name |
Haoyan Chen |
| Organization name |
Renji Hospital
|
| Street address |
145 Shandong Road
|
| City |
Shanghai |
| State/province |
Shanghai |
| ZIP/Postal code |
200001 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA422102 |
| SRA |
SRP126561 |
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