|
| Status |
Public on Sep 03, 2018 |
| Title |
Gene expression changes in human iPSC-derived cardiomyocytes after X-ray irradiation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Within the present study we evaluated hiPSC-CMs as a possible methodological extension for the assessment of organ specific responses to ionizing radiation regarding gene expression changes. We aimed to review the feasibility of hiPSC-CMs as a valid testing model for gene expression changes and to determine alterations within the gene expression pattern of hiPSC-CMs after exposure to X-ray radiation, subsequently.
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| |
|
| Overall design |
2 samples with 3 biological replicates, one sham irradiated, one irradiated with 5 Gy x-ray radiation
|
| |
|
| Contributor(s) |
Becker BV, Ullmann R |
| Citation(s) |
30247079 |
| |
| Submission date |
Dec 04, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Benjamin Becker |
| E-mail(s) |
benjamin3becker@bundeswehr.org
|
| Organization name |
Bundeswehr Institute for Radiobiology
|
| Department |
Genomics II
|
| Street address |
Neuherbergstr. 11
|
| City |
Munich |
| ZIP/Postal code |
80804 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA421022 |
| SRA |
SRP126108 |
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