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| Status |
Public on Nov 30, 2018 |
| Title |
Knockdown of DKK3 decreases malignant property in head and neck squamous cell carcinoma-derived HSC-3 cells. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We hypothesized that DKK3 may exert oncogenic function supecifically in head and neck squamous cell carcinoma (HNSCC).
DKK3 knockdown in HNSCC cell resulted in decreased cellular proliferation, migration, invasion and in vivo tumor growth.
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| Overall design |
Single analysis for each condition (HSC-3 parental cell, HSC-3 shRNA (scramble) and HSC-3 shDKK3 (lentvirus-mediated shRNA targeting to DKK3)
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| Contributor(s) |
Katase N |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Nov 28, 2017 |
| Last update date |
Dec 01, 2018 |
| Contact name |
Satoshi Kondo |
| Organization name |
Toray Industries,Inc.
|
| Street address |
10-1 tebiro 6-chome
|
| City |
Kamakura |
| State/province |
Kanagawa |
| ZIP/Postal code |
248-8555 |
| Country |
Japan |
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| Platforms (1) |
| GPL13915 |
3D-Gene Human Oligo chip 25k V2.1 |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA420015 |
