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Series GSE107105 Query DataSets for GSE107105
Status Public on Jan 17, 2018
Title Microarray analysis of freshly isolated synovial fibroblast subsets in patients with rheumatoid arthritis or osteoarthritis
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Transcriptomics of distinct subpopulations of synovial fibroblasts from osteoarthritis and rheumatoid arthritis arthroplasty tissues.
 
Overall design We gated 7 subsets of synovial fibroblasts by protein surface markers and used microarrays to profile gene expression of cells taken from each gate. This data includes 37 samples from 3 osteoarthritis donors and 3 rheumatoid arthritis donors.
 
Contributor(s) Mizoguchi F
Citation(s) 29476097
NIH grant(s)
Grant ID Grant title Affiliation Name
F31 AR070582 Transcriptomics in synoviocytes defines pathogenesis of rheumatoid arthritis HARVARD UNIVERSITY (MEDICAL SCHOOL) Kamil Slowikowski
R01 AR063759 Discovery and Functional Impact of Common and Rare Variants in RA BRIGHAM AND WOMEN'S HOSPITAL Soumya Raychaudhuri
U01 GM092691 Genetic predictors of response to anti-TNF therapy in rheumatoid arthritis BRIGHAM AND WOMEN'S HOSPITAL Soumya Raychaudhuri
U01 HG009379 Functionally specialized components of disease heritability in ENCODE data HARVARD SCHOOL OF PUBLIC HEALTH Soumya Raychaudhuri
Submission date Nov 17, 2017
Last update date Mar 15, 2019
Contact name Kamil Slowikowski
E-mail(s) kslowikowski@mgh.harvard.edu
Organization name Massachusetts General Brigham
Lab Alexandra-Chloe Villani
Street address Mailstop CNY 149-8, 149 13th Street
City Charlestown
State/province Massachusetts
ZIP/Postal code 02129
Country USA
 
Platforms (1)
GPL16686 [HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version]
Samples (36)
GSM2861345 CD34L_CD90L_Cad11H fibroblasts gated by flow cytometry from donor OA1
GSM2861346 CD34L_CD90H_Cad11H fibroblasts gated by flow cytometry from donor OA1
GSM2861347 CD34L_CD90L_Cad11L fibroblasts gated by flow cytometry from donor OA1
This SubSeries is part of SuperSeries:
GSE109450 Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
Relations
BioProject PRJNA418998

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE107105_RAW.tar 282.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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