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| Status |
Public on Feb 14, 2018 |
| Title |
Expression data from human endothelial cells co-cultured with cancer associated fibroblasts |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Cancer associated fibroblasts (CAFs) have been shown to plays crucial roles in cancer progression. Although increasing evidence demonstrates that CAFs have important roles in modulating the aggressive phenotypes of cancer cells, their effects on the tumor vasculature remain underexplored. We co-cultured TIME human microvascular endothelial cells (MECs) with either primary human ovarian CAFs or normal ovarian fibroblasts (NFs) to evaluate the effects of CAFs on phenotypes of endothelial cells.
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| |
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| Overall design |
RNA samples isolated from TIME cells that had been co-cultured with CAFs or NFs was analyzed using Affymetrix Clariom D human gene expression assays.
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| |
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| Contributor(s) |
Yeung TL, Leung SL, Mok SC |
| Citation(s) |
29251630 |
| Submission date |
Nov 03, 2017 |
| Last update date |
Oct 16, 2018 |
| Contact name |
Tsz-Lun Yeung |
| Organization name |
University of Texas MD Anderson Cancer Center
|
| Department |
Gynecologic Oncology and Reproductive Medicine
|
| Street address |
1515 Holcombe Blvd. Unit 1362
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL23126 |
[Clariom_D_Human] Affymetrix Human Clariom D Assay [transcript (gene) version] |
|
| Samples (5)
|
| GSM2839712 |
TIME cells co-cultured with normal fibroblasts, biological rep1 |
| GSM2839715 |
TIME cells co-cultured with normal fibroblasts, biological rep2 |
| GSM2839717 |
TIME cells co-cultured with cancer associated fibroblasts, biological rep1 |
| GSM2839719 |
TIME cells co-cultured with cancer associated fibroblasts, biological rep2 |
| GSM2839720 |
TIME cells co-cultured with cancer associated fibroblasts, biological rep3 |
|
| Relations |
| BioProject |
PRJNA417079 |
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