|
| Status |
Public on Oct 29, 2018 |
| Title |
Transcript analysis of CD45+Ter119+CD71+ erythroid-like progenitor cells from tumor-bearing mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report the application of RNA sequencing technology for high-throughput profiling of transcriptome in mammalian cells. By this method, we report that the CD45+ EPC transcriptome resembled that of MDSCs. Mechanistically, like MDSCs, production of reactive oxygen species is a major mechanism for EPC-mediated immunosuppression.
|
| |
|
| Overall design |
Examination of CD45+Ter119+CD71+ suppressive immune cell types in comparison to 3 cell types, 3 pathological/physiological status.
|
| |
|
| Contributor(s) |
Zhao L, Long H, He R, Ye L, Li Q, Zhu B |
| Citation(s) |
30297899 |
| |
| Submission date |
Oct 31, 2017 |
| Last update date |
Apr 16, 2021 |
| Contact name |
Qingzhu Jia |
| E-mail(s) |
jiaqingzhu0801@outlook.com
|
| Phone |
152-2333-4184
|
| Organization name |
XinQiao Hospital
|
| Department |
Department of Onoclogy
|
| Street address |
Xinqiao
|
| City |
Chongqing |
| ZIP/Postal code |
400083 |
| Country |
China |
| |
|
| Platforms (1) |
|
| Samples (21)
|
|
| Relations |
| BioProject |
PRJNA416659 |
| SRA |
SRP123227 |
Less...
More...