GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE104836 Query DataSets for GSE104836
Status Public on Oct 12, 2017
Title Differentially expressed LncRNAs and mRNA identified by SEQ analysis in colorectal cancer patients
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
Summary LncRNA plays an important role in gene regulation, but its impact on the pathogenesis of colorectal cancer and the biological function of cancer cells is unclear. In this study, we will use the next generation sequencing technique to study the differences of the expression profiles of lncRNA and mRNA in colorectal cancer tissues, analyzing the differentially expressed genes by GO/KEGG enrichment, and predicting the new lncRNAs’ function. Our results revealed that Comparing with the nontumor colorectal tissues, 1019 lncRNAs (512 upregulated, 507 downregulated) and 3221 mRNAs (1606 upregulated, 1615 downregulated) were differentially expressed in tumor colorectal tissues (fold change>2 and P<0.05).
Overall design lncRNA and mRNA profiles of 10 paired tissues (nontumor and colon cancer tissues) were generated by deep sequencing, in triplicate, using Illumina.
Contributor(s) Wang G, Li M
Citation(s) 30039525
Submission date Oct 11, 2017
Last update date May 15, 2019
Contact name Li Meng
Phone 17732812697
Organization name colon tissues
Street address 12# Jiankang road
City Shijiazhuang
ZIP/Postal code 050011
Country China
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (20)
GSM2808511 29C
GSM2808512 29N
GSM2808513 34C
BioProject PRJNA413956
SRA SRP119775

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE104836_gene_exp.txt.gz 5.4 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap