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| Status |
Public on Nov 04, 2019 |
| Title |
Ribosome-profiling experiments for “Chronic repression by MAF1 supports futile RNA cycling as a mechanism for obesity resistance” |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Other
|
| Summary |
To characterize the translation defects in Maf1-/- samples, we used ribosome profiling on three WT and three Maf1-/- fed livers. Each sample was spiked with a fixed amount of Drosophila S2 Schneider cell material as an internal control for sample-to-sample normalization, and to allow detection of global changes in translation.
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| |
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| Overall design |
Two conditions (WT of Maf1 KO mice), three biological replicates per condition. For each sample, both Ribosome-protected fragments (RPFL) and total RNA fragments (TOTL) were sequenced.
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| Contributor(s) |
Bonhoure N, Praz V, Willis I, Hernandez N |
| Citation(s) |
32686713 |
| |
| Submission date |
Oct 02, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Nicolo Riggi |
| Organization name |
CHUV
|
| Department |
Département de Pathologie Expérimentale
|
| Lab |
Institut universitaire de pathologie
|
| Street address |
Bugnon 25
|
| City |
Lausanne |
| State/province |
VD |
| ZIP/Postal code |
1011 |
| Country |
Switzerland |
| |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE104535 |
Chronic repression by MAF1 supports futile RNA cycling as a mechanism for obesity resistance |
|
| Relations |
| BioProject |
PRJNA412979 |
| SRA |
SRP119310 |
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