|
| Status |
Public on May 18, 2018 |
| Title |
RNA sequencing of prostate cancer and normal tissue from African Americans and European Americans |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Background:African American men (AAM) are at higher risk of being diagnosed with prostate cancer (PCa) and are at higher risk of dying from the disease compared to European American men (EAM). We sought to better understand PCa molecular diversity that may be underlying these disparities. We ran RNA-sequencing data analysis on high-grade PCa to identify genes showing differential tumor versus normal adjacent tissue expression patterns unique to AAM or EAM.
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| |
|
| Overall design |
Matched high-grade (GS≥7(4+3)) prostate tumor and adjacent normal specimens from 16 patients (8 AAM and 8 EAM) were subjected to two replicate runs of RNA-sequencing.
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| |
|
| Contributor(s) |
Mitrea C, Bollig-Fischer A, Girsch E |
| Citation(s) |
29741809 |
| |
| Submission date |
Sep 22, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Aliccia Bollig-Fischer |
| Organization name |
Karmanos Cancer Institute & Wayne State University
|
| Department |
Oncology
|
| Street address |
4100 John R
|
| City |
Detroit |
| ZIP/Postal code |
48201 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (32)
|
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| Relations |
| BioProject |
PRJNA411786 |
| SRA |
SRP118614 |
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