NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE104064 Query DataSets for GSE104064
Status Public on Sep 23, 2017
Title RNAseq data on HDAC Class IIa inhibitor (CHDI-00390576) dosed Q175 mice.
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary WT and Q175 heterozygous (het) mice treated orally twice a day with vehicle (10% HPβCD), and Q175 mice treated with either 30 or 100 mg/kg orally twice a day CHDI-00390576. CHDI-00390576 is a Class IIa HDAC inhibitor. Mice were dosed from 4 weeks to 6 months of age.
 
Overall design Tibialis, striatum, cortex, heart and liver collected N = 8 per group (4M/4F).
 
Contributor(s) Aaronson J, Rosinski J
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Sep 20, 2017
Last update date May 15, 2019
Contact name Jeff Aaronson
E-mail(s) jeff.aaronson@chdifoundation.org
Phone (609) 945-9616
Organization name CHDI
Department Discovery & Systems Biology
Street address 155 Village Boulevard, Suite 200
City Princeton
State/province New Jersey
ZIP/Postal code 08540
Country USA
 
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (160)
GSM2788660 WT_Striatum_Male_Vehicle_rep1
GSM2788661 Het(Q175)_Striatum_Female_Vehicle_rep1
GSM2788662 Het(Q175)_Striatum_Male_Vehicle_rep1
Relations
BioProject PRJNA408141
SRA SRP118346

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE104064_HDGSE37_FPKM.xlsx 41.0 Mb (ftp)(http) XLSX
GSE104064_HDGSE37_counts.xlsx 34.3 Mb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record
| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap