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| Status |
Public on Apr 17, 2018 |
| Title |
Transcriptomic Profiling of Mice with Klf5 Deletion in Context of Oncogenic Kras Expression |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This study used Illumina RNA-sequencing to examine transcriptomic profile of mice with Klf5 knockout in context of oncogenic Kras expression. The study analyzed total RNA extracted from pancreas of mice 2 days after cerulein-induce pancreatitis. In addition, this study include 2 biological replicate of mice with each of the following genotypes: Ptf1aCreERTM, Ptf1aCreERTM;Klf5fl/fl, Ptf1aCerERTM;LSL-KrasG12D, and Ptf1aCreERTM;LSL-KrasG12D;Klf5fl/fl.
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| Overall design |
Transcriptomic profiling of pancreata from 2 Ptf1aCreERTM mice, 2 Ptf1aCreERTM;Klf5fl/fl mice, 2 Ptf1aCerERTM;LSL-KrasG12D mice, and 2 Ptf1aCreERTM;LSL-KrasG12D;Klf5fl/fl mice 2 days after cerulein-induced pancreatitis.
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| |
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| Contributor(s) |
He P, Bialkowska AB |
| Citation(s) |
29248441 |
| |
| Submission date |
Sep 20, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Agnieszka B. Bialkowska |
| E-mail(s) |
Agnieszka.Bialkowska@stonybrookmedicine.edu
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| Organization name |
Stony Brook University
|
| Department |
Dept. of Medicine
|
| Lab |
GI Translational Research Lab
|
| Street address |
HSC-T17 Room 090
|
| City |
Stony Brook |
| State/province |
New York |
| ZIP/Postal code |
11794-8176 |
| Country |
USA |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA408124 |
| SRA |
SRP118318 |
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