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Status |
Public on Oct 15, 2017 |
Title |
CONTROL OF GROWTH AND GUT MATURATION BY HoxD GENES AND THE ASSOCIATED LncRNA Haglr |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
In this work we have analyzed the transcriptomic profiles of E9 mouse embryos. We show that Hoxd1 and Haglr transcripts are absent after targeted deletion of the CpG: 114 island.
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Overall design |
RNA-seq analysis of trunk from the anterior limit of the forelimb bud to the tailbud, aiming to exclude all extra-embryonic, head, cervical and heart tissues. Individuals 443 (wt) and 445 (Del(CpG114) homozygous), were siblings from the same dam, while biological replicates 456 (wt) and 455 (Del(CpG114) homozygous) were siblings from another dam.
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Contributor(s) |
Zakany J, Necsulea A, Duboule D |
Citation(s) |
29042517 |
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Submission date |
Aug 25, 2017 |
Last update date |
Jul 25, 2021 |
Contact name |
Jozsef Zakany |
E-mail(s) |
Jozsef.Zakany@unige.ch
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Phone |
0041223796788
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Organization name |
University of Geneva
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Department |
Genetics and Evolution
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Lab |
Prof. Duboule
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Street address |
30, quai Ernest Ansermet
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City |
Geneva |
State/province |
Geneva |
ZIP/Postal code |
1211 |
Country |
Switzerland |
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Platforms (1) |
GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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Samples (4)
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Relations |
BioProject |
PRJNA400174 |
SRA |
SRP116254 |