|
| Status |
Public on Aug 21, 2017 |
| Title |
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We monitored the transcription changes associated with loss of BRG1, BRM, or both combined I HepG2 cells to understand the functional relationship between two mutually exlusive subunits of SWI/SNF
|
| |
|
| Overall design |
Cells were transduced with shRNA targeting the subunits of interested and subjected to RNAseq.
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| |
|
| Contributor(s) |
Raab J |
| Citation |
Jesse Raab, John S. Runge, Camarie C. Spear, and Terry Magnuson. Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits. bioRxiv 178848, 2017. doi:10.1101/178848
|
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 HD036655 |
Developmental Gene Regulation Via Chromatin Remodeling |
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
Terry R Magnuson |
|
| |
| Submission date |
Aug 11, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Jesse Raab |
| E-mail(s) |
jesse.r.raab@gmail.com
|
| Organization name |
University of North Carolina Chapel Hill
|
| Department |
Genetics
|
| Street address |
120 Mason Farm Rd
|
| City |
Chapel Hill |
| ZIP/Postal code |
27599 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (15)
|
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| This SubSeries is part of SuperSeries: |
| GSE102561 |
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits |
|
| Relations |
| BioProject |
PRJNA398038 |
| SRA |
SRP115304 |
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